Dental pulp regeneration in paediatric dentistry: the role of stem cells.

AIM In the last decade, tissue engineering has undergone enormous expansion in the fields of regenerative medicine and dentistry. In response to mechanical and chemical injuries, the dentine-pulp complex possesses a regenerative ability due to a speci?c population of mesenchymal stem cells, which have been widely described in literature. The postnatal dental pulp also contains progenitor stem cells that participate in dental regeneration. Knowledge of the regenerative potential of these cells is important in terms of understanding and applying their biological and chemical characteristics. CONCLUSION Through the isolation and exploration of the regenerative abilities of these stem cells, new therapeutic possibilities may be possible, opening the way for improving paediatric endodontic therapy.